The Coptic Patriarch died after fighting with liver and lung problems for several years, official MENA news agency reported.
A Coptic Church TV ran a picture of the pope, with a sentence reading "may God rest him in peace between the arms of the saints, " MENA reported.
Church sources said the health condition of the pope deteriorated Saturday morning after suffering a severe heart attack. The pope`s medical team tried to recover him but he passed away.
The Coptic Orthodox Church announced a state of mourning over the pope`s death. It said the funeral prayer would be held on Tuesday at the papal headquarters in the Abbassiya district in Cairo.
Egyptian Prime Minister Kamal el-Ganzouri mourned the death of Shenuda III, describing the pope as a "national figure and a symbol of the Egyptian nationalism, who has earned a great respect from the Egyptian people," MENA reported.
The Muslim Brotherhood, presidential potential Amr Moussa and Egypt`s Mufti Ali Gomaa also mourned the pope`s death. (P012)