"We will closely monitor, analyze and seek to minimize any negative effects of this decision on our economy," Putin said when answering journalists questions after the Shanghai Cooperation Organization (SCO) summit held in Uzbekistan.
"(The Brexit) will eventually have consequences for the United Kingdom, for Europe in general, and for us...The consequences will be of a global nature and they are inevitable," Putin said.
"The markets and currencies have been hit now, will inevitably affect and has already affected the stock exchange indices, also the prices of traditional goods," Putin said.
"But I am confident this will be corrected in the near future," Putin said, stressing the world market would recover in the medium term.
Russia is ready to adjust its relations with European partners if necessary, Putin said when doubting the Brexit would have impact on European sanctions against Russia.
Reiterating Russias willingness to hold dialogues with Europe over sanctions, Putin warned that the Brexit reflected peoples fear on a sharply deteriorating security situation in Europe due to "massive migration flows."
In response to British Prime Minister David Camerons claims that Russia "might be happy" over Brexit, Putin refuted those wording as "baseless" and "flawed attempts to influence the British public opinion."
"Of course we closely followed what was going on, but did not affect this process and did not even attempt to do so," Putin said.
On Friday morning, the Leave camp has won Britains Brexit referendum by obtaining nearly 52 percent of ballots, pulling the country out of the 28-nation European Union (EU) after its 43-year membership, Xinhua reported.